The Entourage Effect: Understanding How Cannabinoids Work Together

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The Entourage Effect is a term coined by Dr. Raphael Mechoulam in 1998 to describe how cannabinoids work together in the body. It’s important that we understand this concept because it can help us determine the appropriate dosage to use for medical purposes, and also personal consumption experience. Cannabis contains more than 400 natural components, including THC and CBD, which are the most abundant of them all. Other compounds include terpenes (e.g., myrcene), flavonoids (e.g., catechins) and other alkaloid molecules like tetrahydrocannabinol acid A (THCA-A). What makes cannabis so unique is that these different compounds have different effects on our endocannabinoid system when combined, which can vary depending on the ratios of each compound.

Terpenes are organic hydrocarbons found in the essential oils of many plants. The cannabis plant produces terpenes to attract pollinators, fight off diseases and protect itself from predators via its unique scent. Terpenes are what give different strains their distinct aroma and flavor. Furthermore, they have been shown to provide a variety of health benefits when consumed or applied topically.

As we understand more about terpenes and cannabinoids, we are finding that consuming different ratios of these compounds produce vastly different effects. For example, Pinene has anti-inflammatory properties and is thought to counteract the paranoia effect caused by THC. Limonene provides stress relief, while Linalool can help with insomnia if consumed in small doses before bedtime. The terpene myrcene has anti-inflammatory, and sedative effects. Working in synergy with THC, the terpene is ideal for patients suffering from: Sleep disorders like insomnia. Pain and bodily discomfort, acting as a powerful muscle relaxant. As an anti-inflammatory, myrcene is helpful for arthritis sufferers.

It’s important to understand more about the various chemicals and how they interact with one another, which is a significant step forward in the business. The more we learn about how the entourage effect works in different cannabis strains, the easier it is to choose which cannabis goods are right for you.